What is amoxicillin and clavulanate potassium? Amoxicillin is a penicillin antibiotic that fights bacteria in the body. Clavulanate potassium is a beta-lactamase inhibitor that helps prevent certain bacteria from becoming resistant to amoxicillin.
Amoxicillin and clavulanate potassium is a combination medicine used to treat many different infections caused by bacteria, such as sinusitis , pneumonia , ear infections, bronchitis, urinary tract infections , and infections of the skin.
Slideshow Sore Throat Remedies And Treatments Important information You should not use this medicine if you have severe kidney disease, if you have had liver problems or jaundice while taking amoxicillin and clavulanate potassium, or if you are allergic to any penicillin or cephalosporin antibiotic, such as Amoxil, Ceftin, Cefzil, Levaquin, Moxatag, Omnicef, and others.
If you switch from one tablet form to another regular, chewable, or extended-release tablet , take only the new tablet form and strength prescribed for you. Amoxicillin and clavulanate may not be as effective or could be harmful if you do not use the exact tablet form your doctor has prescribed. Amoxicillin and clavulanate potassium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Amoxicillin and clavulanate potassium can make birth control pills less effective.
Ask your doctor about using a non-hormone method of birth control such as a condom, diaphragm, spermicide to prevent pregnancy while taking amoxicillin and clavulanate potassium. Before taking this medicine You should not use amoxicillin and clavulanate potassium if you are allergic to it, or if: To make sure amoxicillin and clavulanate potassium is safe for you, tell your doctor if you have ever had: It is not known whether this medicine will harm an unborn baby.
Tell your doctor if you are pregnant or plan to become pregnant. Ask your doctor about using a non-hormonal birth control condom, diaphragm with spermicide to prevent pregnancy. Amoxicillin and clavulanate potassium can pass into breast milk and may affect the nursing baby.
Tell your doctor if you are breast-feeding. Do not give this medicine to a child without medical advice. The liquid or chewable tablet may contain phenylalanine.
Talk to your doctor before using these forms of amoxicillin and clavulanate potassium if you have phenylketonuria PKU. How should I take amoxicillin and clavulanate potassium? Take amoxicillin and clavulanate exactly as prescribed by your doctor. Follow all directions on your prescription label. This medication may rarely cause a severe intestinal condition Clostridium difficile -associated diarrhea due to a type of resistant bacteria.
This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti- diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse.
Tell your doctor immediately if you develop: Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection oral or vaginal fungal infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: The amoxicillin in this combination medication can commonly cause a mild rash that is usually not serious.
However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction. Therefore, seek immediate medical attention if you develop any rash. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects.
You may report side effects to Health Canada at Quick GuideSymptoms of Mono: This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: This reaction requires amoxicillin discontinuation and contra-indicates any subsequent administration. Amoxicillin should be avoided if infectious mononucleosis is suspected since the occurrence of a morbilliform rash has been associated with this condition following the use of amoxicillin.
Jarisch-Herxheimer reaction The Jarisch-Herxheimer reaction has been seen following amoxicillin treatment of Lyme disease see section 4. It results directly from the bactericidal activity of amoxicillin on the causative bacteria of Lyme disease, the spirochaete Borrelia burgdorferi.
Patients should be reassured that this is a common and usually self-limiting consequence of antibiotic treatment of Lyme disease. Overgrowth of non-susceptible microorganisms Prolonged use may occasionally result in overgrowth of non-susceptible organisms.
Antibiotic-associated colitis has been reported with nearly all antibacterial agents and may range in severity from mild to life threatening see section 4. Therefore, it is important to consider this diagnosis in patients who present with diarrhoea during, or subsequent to, the administration of any antibiotics. Should antibiotic-associated colitis occur, amoxicillin should immediately be discontinued, a physician consulted and an appropriate therapy initiated.
Anti-peristaltic medicinal products are contra-indicated in this situation. Prolonged therapy Periodic assessment of organ system functions; including renal, hepatic and haematopoietic function is advisable during prolonged therapy. Elevated liver enzymes and changes in blood counts have been reported see section 4. Anticoagulants Prolongation of prothrombin time has been reported rarely in patients receiving amoxicillin.
Appropriate monitoring should be undertaken when anticoagulants are prescribed concomitantly. Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation see section 4. Crystalluria In patients with reduced urine output, crystalluria has been observed very rarely, predominantly with parenteral therapy.
During the administration of high doses of amoxicillin, it is advisable to maintain adequate fluid intake and urinary output in order to reduce the possibility of amoxicillin crystalluria. In patients with bladder catheters, a regular check of patency should be maintained see section 4.
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