Sildenafil de 25mg

What is in this leaflet: What sildenafil is and what it is used for 2. What you need to know before you take sildenafil 3. How to take sildenafil 4.

Possible side effects 5. How to store sildenafil 6. Contents of the pack and other information 1. What sildenafil is and what it is used for The name of your medicine is Sildenafil 25mg, 50mg or mg film-coated tablets referred to as sildenafil throughout this leaflet.

Sildenafil contains the active substance sildenafil which belongs to a group of medicines called phosphodiesterase type 5 PDE 5 inhibitors. It works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited.

Sildenafil will only help you to get an erection if you are sexually stimulated. Sildenafil is a treatment for adult men with erectile dysfunction, sometimes known as impotence. This is when a man cannot get, or keep a hard, erect penis suitable for sexual activity. What you need to know before you take sildenafil Do not take sildenafil If you are taking medicines called nitrates, as the combination may lead to a dangerous fall in your blood pressure.

If you are not certain, ask your doctor or pharmacist. If you are allergic to sildenafil or any of the other ingredients of this medicine listed in section 6.

If you have a severe heart or liver problem. If you have recently had a stroke or a heart attack, or if you have low blood pressure. If you have certain rare inherited eye diseases such as retinitis pigmentosa. If you have ever had loss of vision due to non-arteritic anterior ischaemic optic neuropathy NAION Warnings and precautions Talk to your doctor, pharmacist or nurse before taking sildenafil If you have sickle cell anaemia an abnormality of red blood cells , leukaemia cancer of blood cells , multiple myeloma cancer of bone marrow.

If you have problems with your heart. Your doctor should carefully check whether your heart can take the additional strain of having sex.

If you currently have a stomach ulcer, or a bleeding problem such as haemophilia. If you experience sudden decrease or loss of vision, stop taking sildenafil and contact your doctor immediately. You should not use sildenafil with any other oral or local treatments for erectile dysfunction. You should not take sildenafil if you do not have erectile dysfunction.

You should not take sildenafil if you are a woman. Special considerations for patients with kidney or liver problems You should tell your doctor if you have kidney or liver problems. Your doctor may decide on a lower dose for you. Children and adolescents Sildenafil should not be given to individuals under the age of Other medicines and sildenafil Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Sildenafil film-coated tablets may interfere with some medicines, especially those used to treat chest pain.

In the event of a medical emergency, you should tell your doctor or pharmacist that you have taken sildenafil and when you did.

Do not take sildenafil with other medicines unless your doctor tells you that you can. You should not take sildenafil if you are taking medicines called nitrates as the combination of these medicines may lead to a dangerous fall in your blood pressure. If you are taking medicines known as protease inhibitors, such as for the treatment of HIV, your doctor may start you on the lowest dose 25mg of sildenafil.

Some patients who take alpha-blocker therapy for the treatment of high blood pressure or prostate enlargement may experience dizziness or light-headedness which may be caused by low blood pressure upon sitting or standing up quickly.

Certain patients have experienced these symptoms when taking sildenafil with alpha-blockers. This is most likely to happen within 4 hours after taking sildenafil. On 6 May , Pfizer , which manufactures Viagra, told the Associated Press they will begin selling the drug directly to patients on its website. Counterfeit medications Counterfeit Viagra, despite generally being cheaper, [60] can contain harmful substances or substances that affect how Viagra works, such as blue printer ink, amphetamines , metronidazole , boric acid , and rat poison.

United States Sildenafil is available as a generic drug in the United States, labelled for pulmonary arterial hypertension. The substance is the same under both trade names. The patent was published in and expired in The patent on Revatio indicated for pulmonary arterial hypertension rather than erectile dysfunction expired in late Generic versions of this low-dose form of sildenafil have been available in the U.

There are no controlled clinical data on the safety or efficacy of VIAGRA in the following groups; if prescribed, this should be done with caution. Prolonged Erection And Priapism Prolonged erection greater than 4 hours and priapism painful erections greater than 6 hours in duration have been reported infrequently since market approval of VIAGRA.

In the event of an erection that persists longer than 4 hours, the patient should seek immediate medical assistance. If priapism is not treated immediately, penile tissue damage and permanent loss of potency could result. VIAGRA should be used with caution in patients with anatomical deformation of the penis such as angulation, cavernosal fibrosis or Peyronie's disease , or in patients who have conditions which may predispose them to priapism such as sickle cell anemia , multiple myeloma , or leukemia.

However, there are no controlled clinical data on the safety or efficacy of VIAGRA in patients with sickle cell or related anemias. Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy NAION , a rare condition and a cause of decreased vision including permanent loss of vision, that has been reported rarely post-marketing in temporal association with the use of all PDE5 inhibitors.

There are no controlled clinical data on the safety or efficacy of VIAGRA in patients with retinitis pigmentosa a minority of these patients have genetic disorders of retinal phosphodiesterases ; if prescribed, this should be done with caution.

When vasodilators are used in combination, an additive effect on blood pressure may occur. Consideration should be given to the following: Patients who demonstrate hemodynamic instability on alpha-blocker therapy alone are at increased risk of symptomatic hypotension with concomitant use of PDE5 inhibitors. Patients should be stable on alpha-blocker therapy prior to initiating a PDE5 inhibitor. In those patients already taking an optimized dose of a PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose.

Stepwise increase in alpha-blocker dose may be associated with further lowering of blood pressure when taking a PDE5 inhibitor. Safety of combined use of PDE5 inhibitors and alpha-blockers may be affected by other variables, including intravascular volume depletion and other anti- hypertensive drugs. Anti-hypertensives VIAGRA has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications.

Adverse Reactions With The Concomitant Use Of Ritonavir The concomitant administration of the protease inhibitor ritonavir substantially increases serum concentrations of sildenafil fold increase in AUC. Data from subjects exposed to high systemic levels of sildenafil are limited. Decreased blood pressure, syncope , and prolonged erection were reported in some healthy volunteers exposed to high doses of sildenafil mg. Such combinations may further lower blood pressure.

Therefore, the use of such combinations is not recommended. However, in vitro studies with human platelets indicate that sildenafil potentiates the antiaggregatory effect of sodium nitroprusside a nitric oxide donor. In addition, the combination of heparin and VIAGRA had an additive effect on bleeding time in the anesthetized rabbit, but this interaction has not been studied in humans.

Counseling of patients about the protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus HIV , may be considered.

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